DKK1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesSK; DKK-1;
ProductOrderD
Clone#2H2
Entrez GenelD22943
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG2b
ImmunogenPurified recombinant fragment of DKK1 expressed in E. Coli.
MW28.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
32-266
Catalog#: 20325
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Images
Western Blot
Figure 1: Western blot analysis using DKK1 mouse mAb against HEK293 (1) and DKK1-hIgGFc transfected HEK293 cell lysate (2).
Figure 1: Western blot analysis using DKK1 mouse mAb against HEK293 (1) and DKK1-hIgGFc transfected HEK293 cell lysate (2).
Product Overview
Description

DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

References (references)
References (references)1. Dev Cell. 2008 Jul;15(1):37-48.
2. Cancer Lett. 2008 Sep 28;269(1):67-77.