Cytokeratin 18 Primary Antibody
Item Information
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Price
Description
Cytokeratin 18, also known as CK18, CYK18, KRT18. Entrez Protein NP_000215. It encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Product Overview
Entrez GenelD
3875
Aliases
CK18; CYK18; KRT18
Clone#
4D11E4
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human Cytokeratin 18 (aa391-483) expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Cancer Genet Cytogenet. 2007 Oct 15;178(2):94-103.
2. J Mol Histol. 2008 Apr;39(2):209-16.
2. J Mol Histol. 2008 Apr;39(2):209-16.
Product Image
Western Blot
Figure 1: Western blot analysis using CK18 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3), Jurkat (4), MCF-7(5), HepG2 (6), A431 (7), HEK293 (8) and K562 (9) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma (A), hepatocarcinoma (B), stomach cancer (C) and colon cancer tissue (D), showing cytoplasmic location with DAB staining using CK18 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.