CLOCK Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesKAT13D; bHLHe8; KIAA0334; CLOCK
ProductOrderC
Clone#8F7
Entrez GenelD9575
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CLOCK expressed in E. Coli.

MW95kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
200-465
Catalog#: 30034
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Images
Western Blot
Figure 1: Western blot analysis using CLOCK mouse mAb against CLOCK(AA: 200-465)-hIgGFc transfected HEK293 cell lysate.
Figure 1: Western blot analysis using CLOCK mouse mAb against CLOCK(AA: 200-465)-hIgGFc transfected HEK293 cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of Hela cells using CLOCK mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Figure 2: Immunofluorescence analysis of Hela cells using CLOCK mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
Product Overview
Description

This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.

References (references)
References (references)1. Chronobiol Int. 2007;24(4):589-97.
2. Neurosci Lett. 2008 Apr 11;435(1):30-3.
3. Virchows Arch. 2009 Apr;454(4):467-74.