CLOCK Primary Antibody
Item Information
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Price
Description
This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
Product Overview
Entrez GenelD
9575
Aliases
KAT13D; bHLHe8; KIAA0334; CLOCK
Clone#
8F7
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CLOCK expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ICC (Immunocytochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Chronobiol Int. 2007;24(4):589-97.
2. Neurosci Lett. 2008 Apr 11;435(1):30-3.
3. Virchows Arch. 2009 Apr;454(4):467-74.
2. Neurosci Lett. 2008 Apr 11;435(1):30-3.
3. Virchows Arch. 2009 Apr;454(4):467-74.
Product Image
Western Blot
Figure 1: Western blot analysis using CLOCK mouse mAb against CLOCK(AA: 200-465)-hIgGFc transfected HEK293 cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of Hela cells using CLOCK mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
For Research Use Only. Not for use in diagnostic procedures.