Mouse Monoclonal Antibody to CLEC2
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Description
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229])
Product Overview
Immunogen
Purified recombinant fragment of human CLEC2 (AA: Extra(58-229)) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CLEC2 mAb against human CLEC2 (AA: Extra(58-229)) recombinant protein. (Expected MW is 23.3 kDa)
Western Blot
Figure 3:Western blot analysis using CLEC2 mAb against HEK293-6e (1) and human CLEC2 (AA: Extra(58-229))-hIgGFc transfected HEK293-6e (2) cell lysate.
Flow cytometric analysis
Figure 4:Flow cytometric analysis of Jurkat cells using CLEC2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded bladder Cancer tissues using CLEC2 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded liver cancer tissues using CLEC2 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.