CHUK Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesIKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha; CHUK
ProductOrderC
Clone#3G12H9
Entrez GenelD1147
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CHUK expressed in E. Coli.
MW85kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
470-746
Catalog#: 30106
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Images
Western Blot
Figure 1: Western blot analysis using CHUK mouse mAb against Raji (1), Jurkat (2), THP-1 (3) and K562 (4) cell lysate.
Figure 1: Western blot analysis using CHUK mouse mAb against Raji (1), Jurkat (2), THP-1 (3) and K562 (4) cell lysate.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of NIH/3T3 cells using CHUK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Figure 2: Immunofluorescence analysis of NIH/3T3 cells using CHUK mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Flow cytometric
Figure 3: Flow cytometric analysis of A549 cells using CHUK mouse mAb (blue) and negative control (red).
Figure 3: Flow cytometric analysis of A549 cells using CHUK mouse mAb (blue) and negative control (red).
Product Overview
Description

This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.

References (references)
References (references)1. Mol Cancer. 2010 Jan 5;9:1.
2. J Infect Dis. 2010 May 1;201(9):1371-80.