CHRNB2 Primary Antibody
Item Information
Catalog #
Size
Price
Description
Neuronal acetylcholine receptors are homo- or heteropentameric complexes composed of homologous alpha and beta subunits. They belong to a superfamily of ligand-gated ion channels which allow the flow of sodium and potassium across the plasma membrane in response to ligands such as acetylcholine and nicotine. This gene encodes one of several beta subunits. Mutations in this gene are associated with autosomal dominant nocturnal frontal lobe epilepsy.
Product Overview
Entrez GenelD
1141
Aliases
EFNL3; nAChRB2
Clone#
2D12A2
Host / Isotype
Mouse / IgG2a
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CHRNB2 (AA: extra 26-233) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Prog Neuropsychopharmacol Biol Psychiatry. 2015 Jun 3;59:84-90.
2.Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2608-12.
2.Cancer Epidemiol Biomarkers Prev. 2009 Oct;18(10):2608-12.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CHRNB2 mAb against human CHRNB2 (AA: extra 26-233) recombinant protein. (Expected MW is 51 kDa)
Western Blot
Figure 3:Western blot analysis using CHRNB2 mAb against HEK293 (1) and CHRNB2 (AA: extra 26-233)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of SH-SY5Y cells using CHRNB2 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.