CHD4 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Product Overview
Entrez GenelD
1108
Aliases
CHD-4; Mi-2b; SIHIWES; Mi2-BETA
Clone#
3D3E9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CHD4 (AA: 1-194) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.J Clin Invest. 2016 Nov 1;126(11):4237-4249.
2.Genes Chromosomes Cancer. 2015 Feb;54(2):122-8.
2.Genes Chromosomes Cancer. 2015 Feb;54(2):122-8.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CHD4 mAb against human CHD4 (AA: 1-194) recombinant protein. (Expected MW is 47.9 kDa)
Western Blot
Figure 3:Western blot analysis using CHD4 mAb against HEK293 (1) and CHD4 (AA: 1-194)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.