CDKN1C Primary Antibody
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Description
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
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ELISA
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng)
WESTERN BLOT
Figure 2: Western blot analysis using CDKN1C mAb against human CDKN1C recombinant protein. (Expected MW is 23.3 kDa)
WESTERN BLOT
Figure 3: Western blot analysis using CDKN1C mAb against HEK293-6e (1) and CDKN1C-hIgGFc transfected HEK293-6e (2) cell lysate.
WESTERN BLOT
Figure 4: Western blot analysis using CDKN1C mouse mAb against SK-Br-3 (1) cell lysate.
FLOW CYTOMETRY
Figure 5: Flow cytometric analysis of Hela cells using CDKN1C mouse mAb (green) and negative control (red).
IMMUNOHISTOCHEMISTRY
Figure 6: Immunohistochemical analysis of paraffin-embedded testis tissues using CDKN1C mouse mAb with DAB staining.
FLOW CYTOMETRY
Figure 7: Flow cytometric analysis of MCF-7 cells using CDKN1C mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.