CDKN1C Primary Antibody
Item Information
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Size
Price
Description
The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.
Product Overview
Entrez GenelD
1028
Aliases
BWS; WBS; p57; BWCR; KIP2; CDKN1C
Clone#
3E3
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CDKN1C expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1. Cell Cycle. 2007 Mar 1;6(5):620-5.
2. Oncogene. 2008 Sep 25;27(43):5651-61.
2. Oncogene. 2008 Sep 25;27(43):5651-61.
Product Image
Western Blot
Figure 1: Western blot analysis using CDKN1C mAb against HEK293 (1) and CDKN1C(AA: 214-316)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.