CDH17 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesHPT1; CDH16; HPT-1
ProductOrderC
Clone#7D10E1
Entrez GenelD1015
FormulationPurified antibody in PBS with 0.05% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CDH17 (AA: extra(600-707)) expressed in E. Coli.
MW92.2kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
IHC_P(Immunohistochemistry)1/200 - 1/1000
WB (Western Blot)1/500 - 1/2000
Sequence
extra(600-707)
Catalog#: 30737
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Images
Western Blot
Figure 1: Western blot analysis using CDH17 mAb against human CDH17 (AA: extra(600-707)) recombinant protein. (Expected MW is 37.9 kDa)
Figure 1: Western blot analysis using CDH17 mAb against human CDH17 (AA: extra(600-707)) recombinant protein. (Expected MW is 37.9 kDa)
Western Blot
Figure 2: Western blot analysis using CDH17 mAb against HEK293 (1) and CDH17 (AA: extra(600-707))-hIgGFc transfected HEK293 (2) cell lysate.
Figure 2: Western blot analysis using CDH17 mAb against HEK293 (1) and CDH17 (AA: extra(600-707))-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemical analysis
Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CDH17 mouse mAb with DAB staining.
Figure 3: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CDH17 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 4: Immunohistochemical analysis of paraffin-embedded colon tissues using CDH17 mouse mAb with DAB staining.
Figure 4: Immunohistochemical analysis of paraffin-embedded colon tissues using CDH17 mouse mAb with DAB staining.
Elisa
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Product Overview
Description

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

References (references)
References (references)1. Cancer Biol Ther. 2013 Mar;14(3):262-70.
2. Mod Pathol. 2008 Nov;21(11):1379-86.