CDC37 Primary Antibody
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Description
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
Product Overview
Immunogen
Purified recombinant fragment of human CDC37 (AA: 241-378) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CDC37 mAb against human CDC37 (AA: 241-378) recombinant protein. (Expected MW is 41.6 kDa)
Western Blot
Figure 3:Western blot analysis using CDC37 mAb against HEK293 (1) and CDC37 (AA: 241-378)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using CDC37 mouse mAb against K562 (1), LNcap (2), A431 (3), and HEK293 (4) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.