CDC25C Primary Antibody
Item Information
Catalog #
Size
Price
Description
Cdc25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It has been highly conserved during evolution and it plays a key role in the regulation of cell division. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Cdc25C is mainly expressed in G2 phase. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
Product Overview
Entrez GenelD
995
Aliases
CDC25; CDC25C
Clone#
1F12
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CDC25C expressed in E. Coli.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Cancer Cell. 2007 Mar;11(3):275-89.
2. Int J Biochem Cell Biol. 2007;39(9):1707-13.
3. Int J Cancer. 2010 May 1;126(9):2199-210.
2. Int J Biochem Cell Biol. 2007;39(9):1707-13.
3. Int J Cancer. 2010 May 1;126(9):2199-210.
Product Image
Western Blot
Figure 1: Western blot analysis using anti-CDC25C mAb against Hela (1), K562 (2), PC-3 (3), HEK293 (4) and Raw264.7 (5) cell lysate.
Immunohistochemical analysis
Figure 2: Immunohistochemical analysis of paraffin-embedded human Testis tissues using anti-CDC25C mouse mAb
For Research Use Only. Not for use in diagnostic procedures.