CD97 Primary Antibody
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
2.PLoS One. 2013 Apr 26;8(4):e62765.
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31542ea.jpg?v=1666703838)
![Figure 2:Western blot analysis using CD97 mAb against human CD97 (AA: extra 419-552) recombinant protein. (Expected MW is 40.9 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31542rwb.jpg?v=1666703838)
![Figure 3:Western blot analysis using CD97 mAb against HEK293 (1) and CD97 (AA: extra 419-552)-hIgGFc transfected HEK293 (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31542twb.jpg?v=1666703838)
![Figure 4:Flow cytometric analysis of HL-60 cells using CD97 mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31542fcm.jpg?v=1666703838)
![Figure 5:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD97 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31542ihc-1.jpg?v=1666703838)
![Figure 6:Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using CD97 mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/31542ihc-2.jpg?v=1666703838)