CD8 Primary Antibody
Item Information
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Description
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
Product Overview
Entrez GenelD
925
Aliases
MAL; p32; Leu2; CD8A
Clone#
RAVB3
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD8 expressed in E. Coli.
Formulation
Purified antibody in PBS containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1. Veillette, A. et al. 1988. Cell 55:301.
Product Image
Flow cytometric
Figure 1: Flow cytometric analysis of blood T cells using CD8 mouse mAb (M2) and negative control (M1).
For Research Use Only. Not for use in diagnostic procedures.