Mouse Monoclonal Antibody to CD62P
Item Information
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Description
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
Product Overview
Entrez GenelD
6403
Aliases
SELP; CD62; GRMP; PSEL; GMP140; LECAM3; PADGEM
Clone#
5E1B12
Host / Isotype
Mouse / IgG1
Immunogen
Purified recombinant fragment of human CD62P (AA: extra 42-208) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.J Thromb Haemost. 2019 May;17(5):771-781. 2.Protein Cell. 2017 Feb;8(2):103-113.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD62P mAb against human CD62P (AA: extra 42-208) recombinant protein. (Expected MW is 45.4 kDa)
Western Blot
Figure 3:Western blot analysis using CD62P mAb against HEK293-6e (1) and CD62P (AA: extra 42-208)-hIgGFc transfected HEK293-6e (2) cell lysate.
Flow cytometric analysis
Figure 4:Flow cytometric analysis of Jurkat cells using CD62P mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.