CD55 Primary Antibody
|Aliases||CR; TC; DAF; CROM|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human CD55 (AA: 238-357) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|ELISA||Propose dilution 1/10000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using CD55 mAb against human CD55 recombinant protein. (Expected MW is 38.5 kDa)
Figure 2: Western blot analysis using CD55 mouse mAb against Raji (1) and K562 (2) cell lysate.
Figure 3: Flow cytometric analysis of K562 cells using CD55 mouse mAb (green) and negative control (red).
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
|References (references)||1.Indian J Med Res. 2011 Jun;133:662-4. |
2.Cell Immunol. 2010;265(2):127-32.