CD49C Primary Antibody
Item Information
Catalog #
Size
Price
Description
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis.
Product Overview
Entrez GenelD
3675
Aliases
ITGA3; VL3A; FRP-2; GAPB3; ILNEB; MSK18; VCA-2; VLA3a; GAP-B3
Clone#
5F1D4
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD49C (AA: extra 63-248) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Cancer Sci. 2013 Sep;104(9):1189-97.2.Br J Cancer. 2013 Jun 25;108(12):2516-24.
Product Image
Western Blot
Figure 1:Western blot analysis using CD49C mAb against human CD49C (AA: extra 63-248) recombinant protein. (Expected MW is 47 kDa)
Elisa
Figure 2:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 3:Western blot analysis using CD49C mAb against HEK293 (1) and CD49C (AA: extra 63-248)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using CD49C mouse mAb against HepG2 (1), HUVEC (2), and HUVE-12 (3) cell lysate.
Flow cytometric
Figure 5:Flow cytometric analysis of HL-60 cells using CD49C mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.