Mouse Monoclonal Antibody to CD42A
Item Information
Catalog #
Size
Price
Description
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Product Overview
Entrez GenelD
2815
Aliases
GPIX,GP9
Clone#
7H1F4
Host / Isotype
Mouse / IgG1
Immunogen
Purified recombinant fragment of human CD42A (AA: extra(17-147)) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1,Case Reports J Thromb Haemost. 2017 Aug;15(8):1646-1654. 2,Case Reports Acta Haematol. 2007;118(3):146-8.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD42A mAb against human CD42A (AA: extra(17-147)) recombinant protein. (Expected MW is 40.3kDa)
Western Blot
Figure 3:Western blot analysis using CD42A mAb against HEK293 (1) and CD42A (AA: extra(17-147))-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric analysis
Figure 4:Flow cytometric analysis of MOLT4 cells using CD42A mouse mAb (green) and negative control (red).
Flow cytometric analysis
Figure 5:Flow cytometric analysis of THP-1 cells using CD42A mouse mAb (green) and negative control (red).
Flow cytometric analysis
Figure 6:Flow cytometric analysis of U937 cells using CD42A mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using CD42A mouse mAb with DAB staining.
Western Blot
Figure 8:Western blot analysis using CD42A mouse mAb against PANC-1 (1),and L1210 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.