CD37 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesGP52-40; TSPAN26; MGC120234
ProductOrderC
Clone#2B8
Entrez GenelD951
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of CD37 expressed in E. Coli.
MW31.7kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman, Mouse
Application
ELISA1/10000
ICC (Immunocytochemistry)1/200 - 1/1000
Sequence
110-241
Catalog#: 20320
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Images
Immunofluorescence analysis
Figure 1: Confocal Immunofluorescence analysis of methanol-fixed BCBL-1 (left) and L1210 (right) cells using CD37 mouse mAb(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
Figure 1: Confocal Immunofluorescence analysis of methanol-fixed BCBL-1 (left) and L1210 (right) cells using CD37 mouse mAb(green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.
Product Overview
Description

CD37, also known as GP52-40, TSPAN26, MGC120234. Enterz Protein NP_001035120. It is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.

References (references)
References (references)1. J Immunol. 2004 Mar 1;172(5):2953-61.
2. J Immunol. 2007 Jan 1;178(1):154-62.