CD352 Primary Antibody

Item Information
Catalog # Size/Concentration Price
31513 100μg $341.00
Specification
AliasesSLAMF6; KALI; NTBA; KALIb; Ly108; NTB-A; SF2000
Clone#2F1C9
Entrez GeneID114836
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human CD352 (AA: extra 22-226) expressed in E. Coli.
MW37.4kDa
Species ReactivityHuman
Application
ELISA1/10000
IHC_P (Immunohistochemistry) 1/200 - 1/1000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
Extra (22-226)
Catalog
31513
$341.00
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Images

Elisa

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Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

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Figure 2:Western blot analysis using CD352 mAb against human CD352 (AA: extra 22-226) recombinant protein. (Expected MW is 49 kDa)

Western Blot

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Figure 3:Western blot analysis using CD352 mAb against HEK293 (1) and CD352 (AA: extra 22-226)-hIgGFc transfected HEK293 (2) cell lysate.

Flow cytometric

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Figure 4:Flow cytometric analysis of HL-60 cells using CD352 mouse mAb (green) and negative control (red).

Immunohistochemical analysis

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Figure 5:Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD352 mouse mAb with DAB staining.

Immunohistochemical analysis

Cell Culture Products

Figure 6:Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using CD352 mouse mAb with DAB staining.

Product Overview
Description

The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

References (references)
References (references) 1.Immunity. 2006 Oct;25(4):559-70.
2.J Biol Chem. 2004 Apr 30;279(18):18662-9.

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