CD339 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.
Product Overview
Entrez GenelD
182
Aliases
JAG1; AGS; AHD; AWS; HJ1; AGS1; JAGL1
Clone#
7C7H2
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD339 (AA: extra 47-212) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Cancer Sci. 2016 Nov;107(11):1705-1716.
2.Gene. 2016 Jan 15;576(1 Pt 3):381-4.
2.Gene. 2016 Jan 15;576(1 Pt 3):381-4.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD339 mAb against human CD339 (AA: extra 47-212) recombinant protein. (Expected MW is 44.6 kDa)
Western Blot
Figure 3:Western blot analysis using CD339 mAb against HEK293 (1) and CD339 (AA: extra 47-212)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using CD339 mouse mAb against Hela (1) cell lysate.
Flow cytometric
Figure 5:Flow cytometric analysis of HL-60 cells using CD339 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.