Mouse Monoclonal Antibody to CD337
Item Information
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Price
Description
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Product Overview
Entrez GenelD
259197
Aliases
NCR3; 1C7; MALS; LY117; NKp30
Clone#
7E4E10
Host / Isotype
Mouse / IgG1
Immunogen
Purified recombinant fragment of human CD337 (AA: extra 19-135) expressed in HEK293-6e cells supernatant.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Oncotarget. 2017 Jul 25;8(30):49548-49563. 2.J Immunol. 2016 Sep 1;197(5):1621-30.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD337 mAb against human CD337 (AA: extra 19-135) recombinant protein. (Expected MW is 43.4 kDa)
Flow cytometric analysis
Figure 3:Flow cytometric analysis of K562 cells using CD337 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.