Mouse Monoclonal Antibody to CD298
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/82317cd77a3066ca07e3266160cf2ee41daebe882c358eca2b180f7c3ee43ab3.jpg?v=1666705289)
![Figure 2:Western blot analysis using CD298 mAb against human CD298 (AA: extra 57-279) recombinant protein. (Expected MW is 51 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/8de55712c6c6defc2ea40608a15406aaebebf2bbc32fdd0473a9e769a3724cdb.jpg?v=1666705289)
![Figure 3:Western blot analysis using CD298 mAb against HEK293-6e (1) and CD298 (AA: extra 57-279)-hIgGFc transfected HEK293-6e (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/dfcb4271e403d5573df350ba113ee5bfd80b7f271c0b769a48dba53b5b3f14af.jpg?v=1666705289)
![Figure 4:Flow cytometric analysis of THP-1 cells using CD298 mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/9198ec8b20170526330ab5d9dd5932e11b37e8233ce681ae6fa6bcf0554ae830.jpg?v=1666705289)