CD269 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Product Overview
Entrez GenelD
608
Aliases
BCMA; TNFRSF17; BCM; TNFRSF13A
Clone#
1D12G9
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human BCMA (AA: QMAGQCSQNEYFDSLc) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Lupus. 2016 May;25(6):582-92.
2.Crit Rev Immunol. 2012;32(4):287-305.
2.Crit Rev Immunol. 2012;32(4):287-305.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD269 mAb against HEK293 (1) and CD269 (AA: 1-184)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 3:Flow cytometric analysis of K562 cells using CD269 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.