Mouse Monoclonal Antibody to CD244

Item Information
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Description

This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Overview
Entrez GenelD
51744
Aliases
2B4; NAIL; Nmrk; NKR2B4; SLAMF4
Clone#
4A6H8
Host / Isotype
Mouse / IgG2b
Immunogen
Purified recombinant fragment of human CD244 (AA: 22-229) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.J Acquir Immune Defic Syndr. 2020 Sep 1;85(1):73-78.2.J Immunother Cancer. 2020 Mar;8(1):e000245.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD244 mAb against HEK293-6e(1) and CD244 (AA: 22-229)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 2:Western blot analysis using CD244 mAb against HEK293-6e(1) and CD244 (AA: 22-229)-hIgGFc transfected HEK293-6e (2) cell lysate.
Flow cytometric analysis
Figure 3:Flow cytometric analysis of THP-1 cells using CD244 mouse mAb (green) and negative control (red).
Figure 3:Flow cytometric analysis of THP-1 cells using CD244 mouse mAb (green) and negative control (red).
Western Blot
Figure 4:Western blot analysis using CD244 mAb against human CD244 (AA: 22-229) recombinant protein. (Expected MW is 49.2 kDa)
Figure 4:Western blot analysis using CD244 mAb against human CD244 (AA: 22-229) recombinant protein. (Expected MW is 49.2 kDa)
For Research Use Only. Not for use in diagnostic procedures.