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CD232 Primary Antibody
|Aliases||PLXNC1; VESPR; PLXN-C1|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human CD232 (AA: extra 35-234) expressed in E. Coli.|
|FCM (Flow Cytometry)||1/200 - 1/400|
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CD232 mAb against human CD232 (AA: extra 35-234) recombinant protein. (Expected MW is 47.2 kDa)
Figure 3:Western blot analysis using CD232 mAb against HEK293 (1) and CD232 (AA: extra 35-234)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Flow cytometric analysis of HL-60 cells using CD232 mouse mAb (green) and negative control (red).
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]
|References (references)||1.Oncogene. 2013 Oct 10;32(41):4941-9.
2.Int Immunol. 2005 Apr;17(4):439-47.