CD222 Primary Antibody

Item Information
Catalog #
Size
Price
Description

This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015]

Product Overview
Immunogen
Purified recombinant fragment of human CD222 (AA: 160-311) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD222 mAb against human CD222 (AA: 160-311) recombinant protein. (Expected MW is 42.9 kDa)
Figure 2:Western blot analysis using CD222 mAb against human CD222 (AA: 160-311) recombinant protein. (Expected MW is 42.9 kDa)
Western Blot
Figure 3:Western blot analysis using CD222 mAb against HEK293 (1) and CD222 (AA: 160-311)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using CD222 mAb against HEK293 (1) and CD222 (AA: 160-311)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.