Mouse Monoclonal Antibody to CD210
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
Product Overview
Entrez GenelD
3587
Aliases
IL10RA; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
Clone#
4D3A9
Host / Isotype
Mouse / IgG1
Immunogen
Purified recombinant fragment of human CD210 (AA: extra 22-235) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Immunohorizons. 2020 Feb 7;4(2):47-56. 2.Zhonghua Er Ke Za Zhi. 2018 Oct 2;56(10):753-758.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD210 mAb against human CD210 (AA: extra 22-235) recombinant protein. (Expected MW is 51.3 kDa)
Western Blot
Figure 3:Western blot analysis using CD210 mAb against HEK293 (1) and CD210 (AA: extra 22-235)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric analysis
Figure 4:Flow cytometric analysis of THP-1 cells using CD210 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.