Mouse Monoclonal Antibody to CD206
Item Information
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Size
Price
Description
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]
Product Overview
Entrez GenelD
4360
Aliases
MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
Clone#
4B11C12
Host / Isotype
Mouse / IgG2a
Immunogen
Purified recombinant fragment of human CD206 (AA: extra(19-218)) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
References
1,Gastroenterology. 2020 May;158(6):1745-1761.2,Sci Rep. 2019 Dec 10;9(1):18750.
Product Image
Western Blot
Figure 1:Western blot analysis using CD206 mAb against human CD206 (AA: extra(19-218)) recombinant protein. (Expected MW is 25.7 kDa)
Western Blot
Figure 2:Western blot analysis using CD206 mAb against HEK293 (1) and CD206 (AA: extra(19-218))-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric analysis
Figure 3:Flow cytometric analysis of MOLT4 cells using CD206 mouse mAb (green) and negative control (red).
Flow cytometric analysis
Figure 4:Flow cytometric analysis of U937 cells using CD206 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 5:Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CD206 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded rectal cancer tissues using CD206 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.