CD20 Primary Antibody

Item Information
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Description

CD20 (MS4A1, membrane-spanning 4-domains, subfamily A, member 1) is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. And it is known to accelerate the G0 to G1 progression induced by IGF-1.

Product Overview
Entrez GenelD
931
Aliases
B1; S7; Bp35; CD20; MS4A2; LEU-16; MGC3969; MS4A1
Clone#
3E9D3C1G3
Host / Isotype
Mouse / IgG
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to aa (EPANPSEKNSPSTQY) of human CD20,conjugated to KLH.
Formulation
Ascitic fluid containing 0.03% sodium azide.
Storage
4°C; -20°C for long term storage
Product Applications
IHC_P(Immunohistochemistry)
1/200 - 1/1000
ICC (Immunocytochemistry)
1/200 - 1/1000
ELISA
1/10000
References
1. Byar K. Semin Oncol Nurs. 2004,Feb, 20 (1 Suppl 1):20-5. Review.
2. Reiners KS. Hansen HP. Krüssmann A. et al. Immunology. 2004,Jun, 112(2):228-36.
Product Image
Immunohistochemical analysis
Figure 1: Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using CD20 mouse mAb.
Figure 1: Immunohistochemical analysis of paraffin-embedded human Tonsil tissues using CD20 mouse mAb.
Immunofluorescence analysis
Figure 2: Immunofluorescence analysis of B lymphocytes using CD20 mouse mAb.
Figure 2: Immunofluorescence analysis of B lymphocytes using CD20 mouse mAb.
For Research Use Only. Not for use in diagnostic procedures.