Mouse Monoclonal Antibody to CD1A
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
![Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/9c924de71cc84369fb2d658d31627bfc096d75eac9cd054194848d1d5f9e4e1e.jpg?v=1666705317)
![Figure 2:Western blot analysis using CD1A mAb against human CD1A (AA: 17-116) recombinant protein. (Expected MW is 39.7 kDa)](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/08c9f89fad25b8f42d51e3fa59232b4d548a3ff4444b926a1faaf14dad5987e3.jpg?v=1666705317)
![Figure 3:Western blot analysis using CD1A mAb against HEK293-6e (1) and CD1A (AA: 17-116)-hIgGFc transfected HEK293-6e (2) cell lysate.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/2803315e1ed0753ca78579a26257ca9f85e9e8458df51b0b7fcc11b28484433c.jpg?v=1666705317)
![Figure 4:Flow cytometric analysis of MOLT4 cells using CD1A mouse mAb (green) and negative control (red).](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/5e1901940f7402f819faed24194caf5344b331619ee68e42d68040470cf96a41.jpg?v=1666705317)
![Figure 5:Immunohistochemical analysis of paraffin-embedded thymus tissues using CD1A mouse mAb with DAB staining.](https://cdn.shopify.com/s/files/1/0604/2661/7019/products/e695025a6809c2817d6468841b90659ac827f5c9b921a2b460f1895be010932c.jpg?v=1666705317)