CD174 Primary Antibody

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Description

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD174 mAb against human CD174 (AA: 199-361) recombinant protein. (Expected MW is 45.5 kDa)
Figure 2:Western blot analysis using CD174 mAb against human CD174 (AA: 199-361) recombinant protein. (Expected MW is 45.5 kDa)
Western Blot
Figure 3:Western blot analysis using CD174 mAb against HEK293 (1) and CD174 (AA: 199-361)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using CD174 mAb against HEK293 (1) and CD174 (AA: 199-361)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD174 mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of HL-60 cells using CD174 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.