CD167 Primary Antibody
Item Information
Catalog #
Size
Price
Description
Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Product Overview
Entrez GenelD
780
Aliases
DDR1;CAK; DDR; NEP; HGK2; PTK3; RTK6; TRKE; EDDR1; MCK10; NTRK4; PTK3A
Clone#
4F2C12
Host / Isotype
Mouse / IgG2b
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD167 (AA: extra 21-176) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Am J Physiol Cell Physiol. 2015 May 1;308(9):C685-96.
2.Med Oncol. 2013;30(3):626.
2.Med Oncol. 2013;30(3):626.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD167 mAb against human CD167 (AA: extra 21-176) recombinant protein. (Expected MW is 43.5 kDa)
Western Blot
Figure 3:Western blot analysis using CD167 mAb against HEK293 (1) and CD167 (AA: extra 21-176)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Ramos cells using CD167 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.