CD157

Item Information
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Description

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

Product Overview
Entrez GenelD
683
Aliases
BST1
Clone#
1A4G4
Host / Isotype
Mouse / Mouse IgG2b
Species Reactivity
Human, Mouse, Rat
Immunogen
Purified recombinant fragment of human CD157 (AA: 82-293) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4℃; -20℃ for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
IHC_P(Immunohistochemistry)
1/200 - 1/1000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Cytometry B Clin Cytom. 2020 Mar;98(2):193-202.
2.Sci Rep. 2017 Nov 21;7(1):15923.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD157 mAb against human CD157 (AA: 82-293) recombinant protein. (Expected MW is 26.9 kDa)
Figure 2:Western blot analysis using CD157 mAb against human CD157 (AA: 82-293) recombinant protein. (Expected MW is 26.9 kDa)
Western Blot
Figure 3:Western blot analysis using CD157 mAb against HEK293-6e (1) and CD157 (AA: 82-293)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using CD157 mAb against HEK293-6e (1) and CD157 (AA: 82-293)-hIgGFc transfected HEK293-6e (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using CD157 mouse mAb against Rat spleen (1) and Mouse spleen (2) cell lysate.
Figure 4:Western blot analysis using CD157 mouse mAb against Rat spleen (1) and Mouse spleen (2) cell lysate.
Immunofluorescence analysis
Figure 5:Flow cytometric analysis of HL-6O cells using CD157 mouse mAb (green) and negative control (red).
Figure 5:Flow cytometric analysis of HL-6O cells using CD157 mouse mAb (green) and negative control (red).
Immunohistochemical analysis
Figure 6:Immunohistochemical analysis of paraffin-embedded brain tissues using CD157 mouse mAb with DAB staining.
Figure 6:Immunohistochemical analysis of paraffin-embedded brain tissues using CD157 mouse mAb with DAB staining.
Immunohistochemical analysis
Figure 7:Immunohistochemical analysis of paraffin-embedded cerebellum tissues using CD157 mouse mAb with DAB staining.
Figure 7:Immunohistochemical analysis of paraffin-embedded cerebellum tissues using CD157 mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.