CD157

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesBST1
Clone#1A9E7
Entrez GenelD683
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG2b
ImmunogenPurified recombinant fragment of human CD157 (AA: 82-293) expressed in E. Coli.
MW35.7kDa
Species ReactivityHuman, Rat
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
82-293
Catalog#: 32320
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD157 mAb against human CD157 (AA: 82-293) recombinant protein. (Expected MW is 26.9 kDa)
Figure 2:Western blot analysis using CD157 mAb against human CD157 (AA: 82-293) recombinant protein. (Expected MW is 26.9 kDa)
Western Blot
Figure 3:Western blot analysis using CD157 mAb against HEK293-6e (1) and CD157 (AA: 82-293)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using CD157 mAb against HEK293-6e (1) and CD157 (AA: 82-293)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunofluorescence analysis
Figure 4:Flow cytometric analysis of HL-60 cells using CD157 mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of HL-60 cells using CD157 mouse mAb (green) and negative control (red).
Western Blot
Figure 5:Western blot analysis using CD157 mouse mAb against Rat spleen (1) cell lysate.
Figure 5:Western blot analysis using CD157 mouse mAb against Rat spleen (1) cell lysate.
Product Overview
Description

Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.

References (references)
References (references)1.Cytometry B Clin Cytom. 2020 Mar;98(2):193-202.
2.Sci Rep. 2017 Nov 21;7(1):15923.