CD143 Primary Antibody

Item Information
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Size
Price
Description

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Product Overview
Entrez GenelD
1636
Aliases
ACE; DCP; ACE1; DCP1
Clone#
3H7E4
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD143 (AA: extra 30-182) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.World J Gastroenterol. 2017 Sep 28;23(36):6705-6714.
2.Biosci Rep. 2017 Apr 28;37(2).
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD143 mAb against human CD143 (AA: extra 30-182) recombinant protein. (Expected MW is 42.9 kDa)
Figure 2:Western blot analysis using CD143 mAb against human CD143 (AA: extra 30-182) recombinant protein. (Expected MW is 42.9 kDa)
Western Blot
Figure 3:Western blot analysis using CD143 mAb against HEK293 (1) and CD143 (AA: extra 30-182)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using CD143 mAb against HEK293 (1) and CD143 (AA: extra 30-182)-hIgGFc transfected HEK293 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.