CD141 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Product Overview
Entrez GenelD
7056
Aliases
THBD; TM; THRM; AHUS6; BDCA3; THPH12
Clone#
2C6C3
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD141 (AA: extra 297-505) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.PLoS One. 2016 Aug 11;11(8):e0160550.
2.Xenotransplantation. 2015 Jul-Aug;22(4):260-72.
2.Xenotransplantation. 2015 Jul-Aug;22(4):260-72.
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD141 mAb against human CD141 (AA: extra 297-505) recombinant protein. (Expected MW is 48.3 kDa)
Western Blot
Figure 3:Western blot analysis using CD141 mAb against HEK293 (1) and CD141 (AA: extra 297-505)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD141 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.