CD141 Primary Antibody
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Description
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Product Overview
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Image
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD141 mAb against human CD141 (AA: extra 297-505) recombinant protein. (Expected MW is 48.3 kDa)
Western Blot
Figure 3:Western blot analysis using CD141 mAb against HEK293 (1) and CD141 (AA: extra 297-505)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of HL-60 cells using CD141 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.