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CD132 Primary Antibody
|Aliases||IL2RG; P64; CIDX; IMD4; SCIDX; IL-2RG; SCIDX1|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human CD132 (AA: extra 23-262) expressed in E. Coli.|
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CD132 mAb against human CD132 (AA: extra 23-262) recombinant protein. (Expected MW is 54.2 kDa)
Figure 3:Western blot analysis using CD132 mAb against HEK293 (1) and CD132 (AA: extra 23-262)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 4:Western blot analysis using CD132 mouse mAb against MOLT4 (1) and U937 (2) cell lysate.
The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
|References (references)||1.Immunogenetics. 2017 Jan;69(1):29-38.
2.J Clin Immunol. 2015 Jul;35(5):449-53.