CD11C Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Product Overview
Entrez GenelD
3687
Aliases
ITGAX; SLEB6
Clone#
6G2D1
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD11C (AA: extra 102-279) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.World J Gastroenterol. 2015 Aug 21;21(31):9403-12.
2.Am J Clin Pathol. 2010 Aug;134(2):271-7.
2.Am J Clin Pathol. 2010 Aug;134(2):271-7.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD11C mAb against human CD11C (AA: extra 102-279) recombinant protein. (Expected MW is 46 kDa)
Western Blot
Figure 3:Western blot analysis using CD11C mAb against HEK293 (1) and CD11C (AA: extra 102-279)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Raji cells using CD11C mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.