CD112 Primary Antibody
Item Information
Catalog #
Size
Price
Description
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product Overview
Entrez GenelD
5819
Aliases
NECTIN2; HVEB; PRR2; PVRL2; PVRR2
Clone#
4A11B12
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human CD112 (AA: extra 58-212) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Mol Cancer. 2013 Jun 12;12:60.
2.Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010 May;26(5):477-9.
2.Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2010 May;26(5):477-9.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using CD112 mAb against human CD112 (AA: extra 58-212) recombinant protein. (Expected MW is 45.4 kDa)
Western Blot
Figure 3:Western blot analysis using CD112 mAb against HEK293 (1) and CD112 (AA: extra 58-212)-hIgGFc transfected HEK293 (2) cell lysate.
Flow cytometric
Figure 4:Flow cytometric analysis of Ramos cells using CD112 mouse mAb (green) and negative control (red).
For Research Use Only. Not for use in diagnostic procedures.