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CAPN2 Primary Antibody
|Aliases||CANP2; mCANP; CANPL2; CANPml|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Immunogen||Purified recombinant fragment of human CAPN2 (AA: 489-700) expressed in E. Coli.|
|WB (Western Blot)||1/500 - 1/2000|
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 2:Western blot analysis using CAPN2 mAb against human CAPN2 (AA: 489-700) recombinant protein. (Expected MW is 50.6 kDa)
Figure 3:Western blot analysis using CAPN2 mAb against HEK293 (1) and CAPN2 (AA: 489-700)-hIgGFc transfected HEK293 (2) cell lysate.
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
|References (references)||1.Biomed Res Int. 2017;2017:2593674.
2.Blood. 2013 May 23;121(21):4340-7.