CAMK2G Primary Antibody
|Aliases||CAMK; CAMKG; CAMK-II|
|Formulation||Purified antibody in PBS with 0.05% sodium azide.|
|Immunogen||Purified recombinant fragment of human CAMK2G (AA: 322-481) expressed in E. Coli.|
|Shipping Information||This product will ship in a box containing blue ice at a temperature of 4°C. Learn More|
|Species Reactivity||Human, Rat|
|IHC_P(Immunohistochemistry)||1/200 - 1/1000|
|FCM (Flow Cytometry)||1/200 - 1/400|
|WB (Western Blot)||1/500 - 1/2000|
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Figure 1: Western blot analysis using CAMK2G mAb against human CAMK2G (AA: 322-481) recombinant protein. (Expected MW is 44 kDa)
Figure 2: Western blot analysis using CAMK2G mAb against HEK293 (1) and CAMK2G (AA: 322-481)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3: Western blot analysis using CAMK2G mouse mAb against PC-12 (1), Jurkat (2), T47D (3), HepG2 (4) cell lysate.
Figure 4: Flow cytometric analysis of Jurkat cells using CAMK2G mouse mAb (green) and negative control (red).
Figure 5: Immunohistochemical analysis of paraffin-embedded prostate cancer tissues using CAMK2G mouse mAb with DAB staining.
Figure 6: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using CAMK2G mouse mAb with DAB staining.
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
|Description||The product of this gene is one of the four subunits of an enzyme which belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a gamma chain. Many alternatively spliced transcripts encoding different isoforms have been described but the full-length nature of all the variants has not been determined. |
|References (references)||1. Blood. 2012 Dec 6;120(24):4829-39. |
2. Diabetologia. 2002 Apr;45(4):580-3.