C3AR1

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesAZ3B; C3AR; HNFAG09
Clone#3B5E1
Entrez GenelD719
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeMouse IgG1
ImmunogenPurified recombinant fragment of human C3AR1 (AA: 161-340) expressed in E. Coli.
MW53.8kDa
Species ReactivityHuman
Application
ELISA1/10000
FCM (Flow Cytometry)1/200 - 1/400
WB (Western Blot)1/500 - 1/2000
Sequence
extra(161-340)
Catalog#: 32288
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Images
Elisa
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using C3AR1 mAb against human C3AR1 (AA: 161-340) recombinant protein. (Expected MW is 46.2 kDa)
Figure 2:Western blot analysis using C3AR1 mAb against human C3AR1 (AA: 161-340) recombinant protein. (Expected MW is 46.2 kDa)
Western Blot
Figure 3:Western blot analysis using C3AR1 mAb against HEK293-6e (1) and C3AR1 (AA: 161-340)-hIgGFc transfected HEK293-6e (2) cell lysate.
Figure 3:Western blot analysis using C3AR1 mAb against HEK293-6e (1) and C3AR1 (AA: 161-340)-hIgGFc transfected HEK293-6e (2) cell lysate.
Immunofluorescence analysis
Figure 4:Flow cytometric analysis of THP-1 cells using C3AR1 mouse mAb (green) and negative control (red).
Figure 4:Flow cytometric analysis of THP-1 cells using C3AR1 mouse mAb (green) and negative control (red).
Product Overview
Description

C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization.

References (references)
References (references)1.Cell Rep. 2019 Sep 3;28(10):2567-2580.e6.
2.ESC Heart Fail. 2018 Oct;5(5):846-857.