C-Kit Primary Antibody
C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Ascitic fluid containing 0.03% sodium azide.
4°C; -20°C for long term storage
Figure 1: Western blot analysis using C-kit mouse mAb against truncated C-kit recombinant protein.
Figure 2: Immunohistochemical analysis of paraffin-embedded maligant mesenchymoma tissues, showing cytoplasmic localization using C-kit mouse mAb with DAB staining.
For Research Use Only. Not for use in diagnostic procedures.