BMP4 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesZYME; BMP2B; OFC11; BMP2B1; MCOPS6; BMP4
ProductOrderB
Clone#10F4B4
Entrez GenelD652
FormulationAscitic fluid containing 0.03% sodium azide.
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human BMP4 expressed in E. Coli.
MW64kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
293 - 408
Catalog#: 20415
Inquire
Contact us to order
Images
Western Blot
Figure 1: Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected HEK293 cell lysate.
Figure 1: Western blot analysis using BMP4 mouse mAb against BMP4-hIgGFc transfected HEK293 cell lysate.
Product Overview
Description

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors.BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

References (references)
References (references)1. Genomics. 1995 Jun 10;27(3):559-60.
2. DNA Seq. 1995;5(5):273-5.
3. J Bone Miner Res. 2009 Dec;24(12):2039-49.
4. Stem Cells Dev. 2009 Nov;18(9):1283-92.