BCL6 Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Product Overview
Entrez GenelD
604
Aliases
BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
Clone#
1H8D10
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.Cancer Lett. 2015 Sep 1;365(2):190-200.
2.BMC Cancer. 2014 Jun 10;14:418.
2.BMC Cancer. 2014 Jun 10;14:418.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 3:Western blot analysis using BCL6 mAb against HEK293 (1) and BCL6 (AA: 147-276)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 3:Western blot analysis using BCL6 mAb against human BCL6 (AA: 147-276) recombinant protein. (Expected MW is 40.5 kDa)
For Research Use Only. Not for use in diagnostic procedures.