AURKA Primary Antibody

Item Information

Catalog #

Size

Price

Description

Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Product Overview

Entrez GenelD

6790

Aliases

AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; AURORA2; MGC34538; AURKA

Clone#

4G10

Host / Isotype

Mouse / IgG1

Species Reactivity

Human, Monkey, Rat

Immunogen

Purified recombinant fragment of human AURKA expressed in E. Coli.

Formulation

Ascitic fluid containing 0.03% sodium azide.

Storage

4°C; -20°C for long term storage

Product Applications

WB (Western Blot)

1/500 - 1/2000

IHC_P(Immunohistochemistry)

1/200 - 1/1000

ELISA

1/10000

References

1. Cell Cycle. 2008 Nov 15;7(22):3525-33.
2. Oncogene. 2008 Nov 20;27(51):6539-49.

Product Image

Western Blot

Figure 1: Western blot analysis using AURKA mouse mAb against HEK293 (1), Sw620 (2), MCF-7 (3), Jurkat (4), Hela (5), HepG2 (6), Cos7 (7) and PC-12 (8) cell lysate.

Immunohistochemical analysis