ATR Primary Antibody
Item Information
Catalog #
Size
Price
Description
The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.
Product Overview
Entrez GenelD
545
Aliases
FRP1; MEC1; SCKL; FCTCS; SCKL1
Clone#
3G6D2
Host / Isotype
Mouse / IgG1
Immunogen
Mouse IgG1
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Product Applications
WB (Western Blot)
1/500 - 1/2000
FCM (Flow Cytometry)
1/200 - 1/400
ELISA
1/10000
References
1.Transl Psychiatry. 2013 Nov 26;3:e326.
2.Head Neck. 2012 May;34(5):674-80.
2.Head Neck. 2012 May;34(5):674-80.
For Research Use Only. Not for use in diagnostic procedures.