ATG4C Primary Antibody
Item Information
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Price
Description
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.
Product Overview
Entrez GenelD
84938
Aliases
APG4C; AUTL1; AUTL3; APG4-C
Clone#
2E10H7
Host / Isotype
Mouse / IgG1
Species Reactivity
Human
Immunogen
Purified recombinant fragment of human ATG4C (AA: 321-458) expressed in E. Coli.
Formulation
Purified antibody in PBS with 0.05% sodium azide
Storage
4°C; -20°C for long term storage
Product Applications
WB (Western Blot)
1/500 - 1/2000
ELISA
1/10000
References
1.J Biol Chem. 2007 Jun 22;282(25):18573-83.
2.J Biol Chem. 2003 Feb 7;278(6):3671-8.
2.J Biol Chem. 2003 Feb 7;278(6):3671-8.
Product Image
Elisa
Figure 1: Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western Blot
Figure 2:Western blot analysis using ATG4C mAb against human ATG4C (AA: 321-458) recombinant protein. (Expected MW is 42.2 kDa)
Western Blot
Figure 3:Western blot analysis using ATG4C mAb against HEK293 (1) and ATG4C (AA: 321-458)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using ATG4C mouse mAb against HEK293 (1) and MOLT4 (2) cell lysate.
For Research Use Only. Not for use in diagnostic procedures.