ATG16L1 Primary Antibody

Item Information
Catalog #Size/ConcentrationPrice
Specification
AliasesIBD10; WDR30; APG16L; ATG16A; ATG16L
ProductOrderA
Clone#8F8C2
Entrez GenelD55054
FormulationPurified antibody in PBS with 0.05% sodium azide
HostMouse
IsotypeIgG1
ImmunogenPurified recombinant fragment of human ATG16L1 (AA: 11-257) expressed in E. Coli.
MW68.3kDa
Shipping InformationThis product will ship in a box containing blue ice at a temperature of 4°C. Learn More
Species ReactivityHuman
Application
ELISA1/10000
WB (Western Blot)1/500 - 1/2000
Sequence
11-257
Catalog#: 30848
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Images
Elisa
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western Blot
Figure 2:Western blot analysis using ATG16L1 mAb against human ATG16L1 (AA: 11-257) recombinant protein. (Expected MW is 55.8 kDa)
Figure 2:Western blot analysis using ATG16L1 mAb against human ATG16L1 (AA: 11-257) recombinant protein. (Expected MW is 55.8 kDa)
Western Blot
Figure 3:Western blot analysis using ATG16L1 mAb against HEK293 (1) and ATG16L1 (AA: 11-257)-hIgGFc transfected HEK293 (2) cell lysate.
Figure 3:Western blot analysis using ATG16L1 mAb against HEK293 (1) and ATG16L1 (AA: 11-257)-hIgGFc transfected HEK293 (2) cell lysate.
Western Blot
Figure 4:Western blot analysis using ATG16L1 mouse mAb against Hela (1) cell lysate.
Figure 4:Western blot analysis using ATG16L1 mouse mAb against Hela (1) cell lysate.
Product Overview
DescriptionThe protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.
References (references)
References (references)1.Autophagy. 2012 Sep;8(9):1387-8.
2.Inflamm Bowel Dis. 2011 Jul;17(7):1635-6.